Ehsaas Madan, founder of The Loony Scientist in conversation about Organ-on-a-chip technology with Dr. Prajakta Dandekar Jain. Dr. Jain is the UGC Assistant Professor in Engineering Sciences at the Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai. She is a Ramanujan Fellow and her research interests include 3D cell Culture, Nanofibres and Tissue Engineering, RNA therapeutics and Nanomedicine, High Throughput cellular models for toxicity, efficacy and bioassays, Green biotechnology and Green Chemistry. We take a deep dive....Understanding the newer technologies in 3D cell culture and especially Organ-on-chip technology. And also get her perspective on research experience in India vs International experience. The questions we discussed: 00:00 Could you please tell a bit more about yourself and your journey. 01:45 What does in-vivo and in-vitro mean. And what is considered better? 05:21 Why is 3D cell culture considered better than 2D cell culture? What techniques currently exist to culture cells into 3D structures? 13:09 What is organ-on-chip technology and how is it created? 16:34 Can you please give us some examples of organs-on-a-chip that have been developed? 19:25 Can this technology potentially replace animal testing? And also lead to personalised medicine? 22:19 Can multiple organs be integrated onto a single chip, finally achieving a human-on-a-chip? 24:12 What is the most exciting project that you have worked on? 27:14 Your work also focuses on green biotechnology. Could you please tell us a bit about it? 29:14 Were you always interested in research or did this interest develop later. 30:44 How would you compare your research experience in India vs abroad? 33:30 What would your advice be to anybody who is interested in Stem as a career path? The purpose of this channel is to establish open communication about topics in STEM with specialists in their respective fields, to have a more meaningful impact, to go wider and deeper into topics in STEM. The Loony Scientist is a not-for-profit initiative created to spread the love for STEM. Reach out to us if you have any questions or suggestions or if you would like to collaborate on a project together. Please like and subscribe to get updates on our latest episodes Visit our website https://www.theloonyscientist.com Follow us on Instagram 👉🏼https://www.instagram.com/the.loony.scientist LinkedIn http://linkedin.com/in/ehsaasmadan Intro music credit Music: Last Summer Musician: @iksonmusic

Ehsaas Madan, founder of The Loony Scientist in conversation with India’s top vaccine scientist Dr. Gagandeep Kang! Known as India’s “vaccine godmother”, awarded the Infosys prize and the first Indian woman to be elected as a Fellow of the Royal Society. We take a deep dive....Decoding Viruses and vaccines, the COVID virus, its mutations, and vaccines. We also get her perspective on women in STEM. Questions we discussed and time :- 0:00 Intro 0:22 About Dr. Gagandeep Kang and her journey. 1:22 About the rotavirus and how these Vaccines were developed. 7:50 What is the deadliest virus that she has come across in her work over the years as a virologist? 12:20 About the SARS-COV-2 genome structure and how do mutations occur? 18:10 There are so many different COVID-19 Vaccines that are now available. We discuss the technology behind these vaccines, and which vaccine is the most pathbreaking scientifically? 24:00 What helped us to develop vaccines so quickly for SARS CoV-2? 30:25 About mRNA technology that enabled the mRNA vaccines development for SARS-COV-2? 34:08 Which vaccine will have better efficacy on COVID-19 variants of concern? 36:33 In a recent development, FDA has denied the approval for covaxin under Emergency use authorisation, which has raised some concerns. Should we be worried despite the fact that it is based on conventional technology? 38:44 Is it advisable to take the antibody test before taking the second dose of The COVID vaccine and is there an optimum antibody range? 43:08 The Pfizer vaccine has been recently approved by the FDA for children over 12 years of age. And that’s a very positive step towards normalcy. Since the Pfizer vaccine is not available in India, will other vaccines that are available in India be safe for children? 47:00 About CEPI and Disease X. 51:20 What has been the most defining moment in her professional life? 55:20 Why do we see fewer women in positions of prominence in STEM? 1:01:01 Did she personally ever face gender bias in her journey to the top and what would her advice be to women in STEM? 1:03:28 Women are underrepresented in STEM fields but have made significant contributions and played leading roles in the scientific research and the development of COVID vaccines. 1:06:48 About her childhood and what was her inspiration? 1:09:52 Advice to anyone, especially girls, who want to pursue a career in microbiology and virology. 1:12:37 Will we ever be able to go back to school? The purpose of this channel is to establish open communication about topics in STEM with specialists in their respective fields, to have a more meaningful impact, to go wider and deeper into topics in STEM. The Loony Scientist is a not-for-profit initiative created to spread the love for STEM. Reach out to us if you have any questions or suggestions or if you would like to collaborate on a project together. Please like and subscribe to get updates on our latest episodes Visit our website https://www.theloonyscientist.com Follow us on Instagram 👉🏼https://www.instagram.com/the.loony.scientist LinkedIn http://linkedin.com/in/ehsaasmadan Intro music credit Music: Last Summer Musician: @iksonmusic

What are Gene editing, Crispr, and cell therapy? Can Human DNA be Altered? In this video, we explore the latest innovations and what's new in Biotechnology. Especially for students curious about the pathbreaking research in Genetic engineering and science. Ehsaas Madan, the founder of The Loony Scientist, spoke with Dr. Himanshu Gadgil, Chief Scientific Officer and Full Time Director at Enzeze Biosciences Ltd. This channel aims to establish open communication about topics in STEM with specialists in their respective fields, have a more meaningful impact, and go wider and deeper into topics in STEM. The Loony Scientist is a not-for-profit initiative created to spread the love for STEM. Reach out to us if you have any questions or suggestions or if you would like to collaborate on a project together. Thank you so much for watching and please don't forget to like and subscribe :) 👉🏽Watch the first part of this episode where we discussed - what are Biosimilars? https://youtu.be/P123AiQRrIs Visit our website https://www.theloonyscientist.com Follow us on Instagram 👉🏼https://www.instagram.com/the.loony.scientist LinkedIn http://linkedin.com/in/ehsaasmadan Intro music credit Music: Last Summer Musician: @iksonmusic

What are Biosimilars? What does the future of Biosimilars look like? What's new in Biotechnology? Ehsaas Madan, The Loony Scientist in conversation with Dr. Himanshu Gadgil, Chief Scientific Officer and Director at Enzeze Biosciences Ltd. The purpose of this channel is to establish open communication about topics in STEM with specialists in their respective fields, to have a more meaningful impact, to go wider and deeper into topics in STEM. The Loony Scientist is a not-for-profit initiative created to spread the love for STEM. Reach out to us if you have any questions or suggestions or if you would like to collaborate on a project together. Thank you so much for watching and please don't forget to like and subscribe :) In the next video, we will discuss Gene Editing, Gene therapy and Cell therapy. Visit our website https://www.theloonyscientist.com Follow us on Instagram 👉🏼https://www.instagram.com/the.loony.scientist LinkedIn http://linkedin.com/in/ehsaasmadan Intro music credit Musician: @iksonmusic Created with Movavi Video Editor Plus https://www.movavi.com/video-editor-plus/?c=veplus21

If you are curious and always wanting to learn about new concepts in Science, technology, engineering, and maths, you have reached the right place. The loony Scientist is an initiative to explore STEM concepts at a deeper level and nurture budding scientists. Let us take you on a journey understanding the new technologies, latest innovations, and path-breaking research with specialists in their respective fields. Be curious with Ehsaas Madan, the founder of THE LOONY SCIENTIST and a student in 11th grade in Sanskriti School, Delhi. The Loony Scientist is a not-for-profit and for the 'love for science,' organization and all proceeds from any sales, workshops, and sponsorships will go towards buying Lab equipment for organizations for the underprivileged. Have an idea, want to ask a question, curious about something or want to collaborate.....reach out to us and we will be more than happy. Thank you so much for watching and please don't forget to like and subscribe :) follow us on Instagram https://instagram.com/the.loony.scientist?utm_medium=copy_link visit our website www.theloonyscientist.com Music: Balloon Musician: @iksonmusic

What is Artificial Intelligence? In this video, we explore what is Data Science, Machine Learning, and Deep Learning. Especially for students curious about computer science and who want to explore a future career in the field of Science, Technology, Engineering and Maths Ehsaas Madan, the founder of The Loony Scientist, spoke with Mr. Anurag Sahay, VP and Global Business Unit Head - AI and Data Sciences at Nagarro, Adjunct Faculty at Plaksha University This channel aims to establish open communication about topics in STEM with specialists in their respective fields, have a more meaningful impact, and go wider and deeper into topics in STEM. The Loony Scientist is a not-for-profit initiative created to spread the love for STEM. Reach out to us if you have any questions or suggestions or if you would like to collaborate on a project together. Thank you so much for watching and please don't forget to like and subscribe :) Visit our website https://www.theloonyscientist.com Follow us on Instagram 👉🏼https://www.instagram.com/the.loony.scientist LinkedIn http://linkedin.com/in/ehsaasmadan Created with Movavi Video Editor Plus https://www.movavi.com/video-editor-plus/?c=veplus21